Full protein name | Chromobox protein homolog 1;HP1Hsbeta;Heterochromatin protein 1 homolog beta;Heterochromatin protein p25;M31;Modifier 1 protein;p25beta |
Gene name | CBX1;CBX |
Species | Homo sapiens |
Localization | Nucleus. |
Description | Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. |
GO term | GO:0003682; chromatin binding; TAS:ProtInc. GO:0019899; enzyme binding; IPI:UniProtKB. GO:1990226; histone methyltransferase binding; IPI:BHF-UCL. GO:0042802; identical protein binding; IEA:Ensembl. |
Full sequence length | 185 |
Database linked | MobiDB :P83916  DisProt :DP02856  IDEAL :IID00275  OMIM :604511   |
IDR Region | 1 185      |
LCR Region | 1 185      |