| Full protein name | Son of sevenless homolog 1 |
| Gene name | SOS1 |
| Species | Homo sapiens |
| Localization | N/A |
| Description | Promotes the exchange of Ras-bound GDP by GTP. Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity. |
| GO term | GO:0003677; DNA binding; IEA:InterPro. GO:0005096; GTPase activator activity; TAS:ProtInc. GO:0005085; guanyl-nucleotide exchange factor activity; EXP:Reactome. GO:0046982; protein heterodimerization activity; IEA:InterPro. GO:0017124; SH3 domain binding; IEA:Ensembl. |
| Full sequence length | 1333 |
| Database linked | MobiDB :Q07889 DisProt :DP01534 OMIM :182530 |
| IDR Region | 1 1333 |
| LCR Region | 1 1333 |