| Full protein name | Protein numb |
| Gene name | numb;CG3779 |
| Species | Drosophila melanogaster |
| Localization | Nucleus; Cytoplasm, cell cortex. |
| Description | Required in determination of cell fate during sensory organ formation in embryos. Restricts developmental potential and promote maturation of intermediary neuronal progenitor (INP) cells probably acting as an antagonist of Notch signaling. Numb PTB domain, using two distinct binding surfaces, recognizes repeating motifs within Pon in a previously unrecognized mode. The multivalent Numb-Pon interaction leads to high binding specificity and liquid-liquid phase separation of the complex. |
| GO term | GO:0005524; ATP binding; IEA:UniProtKB-KW. GO:0005112; Notch binding; IDA:FlyBase. |
| Full sequence length | 556 |
| Database linked | MobiDB :P16554 |
| IDR Region | 1 556 |
| LCR Region | 1 556 |