Full protein name | Chromobox protein homolog 2 |
Gene name | CBX2 |
Species | Homo sapiens |
Localization | Nucleus; Chromosome. |
Description | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. CBX2 is the protein that condenses chromatin through the highly basic residues within the IDR. |
GO term | GO:0003682; chromatin binding; IEA:Ensembl. GO:0003677; DNA binding; IEA:UniProtKB-KW. GO:0035064; methylated histone binding; IBA:GO_Central. |
Full sequence length | 532 |
Database linked | MobiDB :Q14781  OMIM :602770   |
IDR Region | 1 532      |
LCR Region | 1 532      |