CBX2 Q14781

Full protein name Chromobox protein homolog 2
Gene name CBX2
Species Homo sapiens
Localization Nucleus; Chromosome.
Description Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. CBX2 is the protein that condenses chromatin through the highly basic residues within the IDR.
GO term GO:0003682; chromatin binding; IEA:Ensembl.
GO:0003677; DNA binding; IEA:UniProtKB-KW.
GO:0035064; methylated histone binding; IBA:GO_Central.
Full sequence length 532
Database linked MobiDB :Q14781  OMIM :602770  
IDR Region1 0-0 532     
LCR Region1 70-82 101-127 195-209 265-280 464-478 532