Caprin-1;Cell cycle-associated protein 1;Cytoplasmic activation-and proliferation-associated protein 1;GPI-anchored membrane protein 1;GPI-anchored protein p137, GPI-p137, p137GPI;Membrane component chromosome 11 surface marker 1;RNA granule protein 105
Gene name
CAPRIN1;GPIAP1;GPIP137;M11S1;RNG105
Species
Homo sapiens
Localization
Cytoplasm, cytosol; Cell projection, dendrite.
Description
CARPIN1（also called GPIAP1, GPIP137, M11S1, RNG105）Many cytoplasmic condensates are involved in translational regulation, including stress gran- ules, P-bodies, and neuronal granules. These condensates share a common set of protein com- ponents that are enriched for PTMs, which is suggestive of shared mechanisms of transla- tional regulation. Two highly expressed RNA- binding proteins colocalized in many common cytoplasmic condensates are CAPRIN1. Both proteins are functionally involved in mRNA stability and translational repression and are biologically linked to pathways involved in synaptic plasticity.