| Full protein name | DNA replication factor Cdt1;Double parked homolog;DUP |
| Gene name | CDT1 |
| Species | Homo sapiens |
| Localization | Nucleus.Chromosome, centromere, kinetochore. |
| Description | Required for both DNA replication and mitosis . DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC). Required also for mitosis by promoting stable kinetochore-microtubule attachments. Potential oncogene (By similarity). |
| GO term | GO:0003682; chromatin binding; IDA:CAFA. GO:0003677; DNA binding; ISS:UniProtKB. GO:0070182; DNA polymerase binding; IBA:GO_Central. |
| Full sequence length | 546 |
| Database linked | MobiDB :Q9H211 DisProt :DP01193 FuzDB :FC00180 OMIM :605525 |
| IDR Region | 1 546 |
| LCR Region | 1 546 |