| Full protein name | DnaJ homolog subfamily B member 1;DnaJ protein homolog 1;Heat shock 40 kDa protein 1;Human DnaJ protein 1 |
| Gene name | DNAJB1;DNAJ1, HDJ1, HSPF1 |
| Species | Homo sapiens |
| Localization | Cytoplasm. Nucleus. Nucleus, nucleolus. |
| Description | Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). |
| GO term | GO:0001671; ATPase activator activity; IDA:UniProtKB. GO:0051117; ATPase binding; IPI:BHF-UCL. GO:0045296; cadherin binding; HDA:BHF-UCL. GO:0051087; chaperone binding; IPI:UniProtKB. GO:0030544; Hsp70 protein binding; IPI:BHF-UCL. GO:0044183; protein folding chaperone; IEA:Ensembl. GO:0003714; transcription corepressor activity; IDA:UniProtKB. GO:0051082; unfolded protein binding; IDA:UniProtKB. |
| Full sequence length | 340 |
| Database linked | MobiDB :P25685 IDEAL :IID00446 OMIM :604572 |
| IDR Region | 1 340 |
| LCR Region | 1 340 |