Histone H1.4 P10412

Full protein name Histone H1.4;Histone H1b;Histone H1s-4
Gene name H1-4 ;H1F4 ,HIST1H1E
Species Homo sapiens
Localization Nucleus. Chromosome.
Description Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
GO term GO:0043531; ADP binding; IEA:Ensembl.
GO:0016208; AMP binding; IEA:Ensembl.
GO:0005524; ATP binding; IEA:Ensembl.
GO:0005509; calcium ion binding; IEA:Ensembl.
GO:0031490; chromatin DNA binding; IMP:UniProtKB.
GO:0032564; dATP binding; IEA:Ensembl.
GO:0003690; double-stranded DNA binding; IBA:GO_Central.
GO:0005525; GTP binding; IEA:Ensembl.
GO:0031492; nucleosomal DNA binding; IBA:GO_Central.
GO:0003723; RNA binding; HDA:UniProtKB.
Full sequence length 219
Database linked MobiDB :P10412  IDEAL :IID00538  OMIM :142220  
IDR Region1 21-36 219     
LCR Region1 4-16 21-37 59-69 109-218 219