Full protein name | Histone H1.4;Histone H1b;Histone H1s-4 |
Gene name | H1-4 ;H1F4 ,HIST1H1E |
Species | Homo sapiens |
Localization | Nucleus. Chromosome. |
Description | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). |
GO term | GO:0043531; ADP binding; IEA:Ensembl. GO:0016208; AMP binding; IEA:Ensembl. GO:0005524; ATP binding; IEA:Ensembl. GO:0005509; calcium ion binding; IEA:Ensembl. GO:0031490; chromatin DNA binding; IMP:UniProtKB. GO:0032564; dATP binding; IEA:Ensembl. GO:0003690; double-stranded DNA binding; IBA:GO_Central. GO:0005525; GTP binding; IEA:Ensembl. GO:0031492; nucleosomal DNA binding; IBA:GO_Central. GO:0003723; RNA binding; HDA:UniProtKB. |
Full sequence length | 219 |
Database linked | MobiDB :P10412  IDEAL :IID00538  OMIM :142220   |
IDR Region | 1 219      |
LCR Region | 1 219      |