| Full protein name | Nuclear pore complex protein Nup98-Nup96 |
| Gene name | NUP98;ADAR2 |
| Species | Homo sapiens |
| Localization | Nucleus membrane; Peripheral membrane protein;Nucleoplasmic side. Nucleus, nuclear pore complex. Nucleus, nucleoplasm. |
| Description | Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. NUP98 and NUP96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC. In cooperation with DHX9, plays a role in transcription and alternative splicing activation of a subset of genes . Involved in the localization of DHX9 in discrete intranuclear foci (GLFG-body) . |
| GO term | GO:0003729; mRNA binding; IMP:UniProtKB. GO:0008139; nuclear localization sequence binding; IEA:Ensembl. GO:1990841; promoter-specific chromatin binding; IMP:UniProtKB. GO:0008236; serine-type peptidase activity; IEA:UniProtKB-KW. GO:0017056; structural constituent of nuclear pore; IMP:UniProtKB. GO:0003713; transcription coactivator activity; IMP:UniProtKB. GO:0005215; transporter activity; TAS:ProtInc. |
| Full sequence length | 1817 |
| Database linked | MobiDB :P52948 DisProt :DP02123 OMIM :601021 |
| IDR Region | 1 1817 |
| LCR Region | 1 1817 |