| Full protein name | ELKS/Rab6-interacting/CAST family member 1;CAZ-associated structural protein 2;Rab6-interacting protein 2 |
| Gene name | Erc1;Cast2, Elks, Rab6ip2 |
| Species | Rattus norvegicus |
| Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Membrane; Peripheral membrane protein. Golgi apparatus membrane;Peripheral membrane protein. Cell junction, synapse, presynaptic active zone. |
| Description | Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex (By similarity).May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. |
| GO term | GO:0030165; PDZ domain binding; IDA:RGD. GO:0031267; small GTPase binding; ISS:ParkinsonsUK-UCL. GO:0098882; structural constituent of presynaptic active zone; ISO:RGD. GO:0099635; voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels; ISO:RGD. |
| Full sequence length | 948 |
| Database linked | MobiDB :Q811U3 |
| IDR Region | 1 948 |
| LCR Region | 1 948 |